Semaglutide

What is Semaglutide?

Semaglutide injection is in a class of medications called incretin mimetics. It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood into other body tissues where it is used for energy.

How does Semaglutide cause weight loss?

Semaglutide weight loss works by increasing the amount of insulin produced by the pancreas and decreasing the amount of glucagon produced by the liver. This combination results in reduced hunger and increased energy levels, leading to weight loss.

How much weight can you lose with Semaglutide?

The Semaglutide Treatment Effect in People With Obesity (STEP) trials have shown the efficacy of semaglutide for the treatment of obesity. In large RCTs, patients receiving semaglutide, 2.4 mg, lost a mean of 6% of their weight by week 12 and 12% of their weight by week 28.

Semaglutide is one of the most effective treatments for obesity

Semaglutide works by making people feel full sooner and suppressing the appetite so people do not feel as hungry. One of the ways it does this is by slowing emptying of the stomach so there is a feeling of satiety. Anyone with obesity defined as a Body Mass Index (BMI) of 30 and above or a BMI of 27 and above who is experiencing weight-related complications such as hypertension or type 2 diabetes would be a good candidate to use this medication.

According to Dr. Kathleen Dungan, an endocrinologist in the Division of Endocrinology, Diabetes & Metabolism at The Ohio State University Wexner Medical Center, there are several potential benefits to using semaglutide. It is one of the most effective treatments available for either condition, outside of bariatric surgery, there is evidence that the use of semaglutide may reduce the risk for developing diabetes and may be particularly useful in individuals who have prediabetes.

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